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dievini Hopp BioTech holding GmbH & Co. KG
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  • CompanyCosmo Pharmaceuticals NV

December 21, 2022: Cosmo Pharmaceuticals NV

Cosmo and Hyphens Announce Signing of License and Supply Agreements for Winlevi® in Southeast Asia

Cosmo Pharmaceuticals N.V. (“Cosmo”) and Hyphens Pharma International Limited (SGX: 1J5) (“Hyphens”) today announced the signing of License and Supply Agreements for Winlevi® (clascoterone) cream 1% in Southeast Asia.

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Cosmo Pharmaceuticals NV

December 16, 2022: Heidelberg Pharma AG

Heidelberg Pharma Signs Research and Exclusive Option Agreement with Binghamton University on Immunostimulatory Technology Platform

Heidelberg Pharma AG today announced that it has entered into a research and exclusive option agreement with Binghamton University, State University of New York, Binghamton, NY, USA, related to a novel and proprietary immunostimulatory technology platform.

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Heidelberg Pharma AG

December 14, 2022: Heidelberg Pharma AG

Encouraging Clinical Data from Two Antibody Drug Conjugates Based on Heidelberg Pharma’s ATAC Technology Presented at the ASH Annual Meeting 2022

Heidelberg Pharma AG (FSE: HPHA) today announced that initial clinical data from two Antibody Drug Conjugates (ADCs) based on the Company’s proprietary ATAC technology was presented at the ASH Annual Meeting 2022. Heidelberg Pharma showed preliminary safety data from the clinical trial with its candidate HDP-101 and partner Magenta Therapeutics, Cambridge, MA, USA, (Magenta) (NASDAQ: MGTA) presented in an oral session preliminary positive safety and initial efficacy data from its clinical trial with the ATAC candidate MGTA-117.

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Heidelberg Pharma AG

December 14, 2022: CureVac AG

CureVac Members of Management Sell Shares to Cover Tax Obligations from Long Term Incentive Program

CureVac N.V., a global biopharmaceutical company developing a new class of transformative medicines based on messenger ribonucleic acid (“mRNA”), today announced that Chief Executive Officer Franz-Werner Haas, Chief Financial Officer Pierre Kemula and Interim Chief Development Officer Ulrike Gnad-Vogt sold an aggregate of 103,775 CureVac common shares. The sales were made solely to cover tax and social security obligations from a legacy Virtual Stock Option Plan (Prior VSOP), which granted virtual options to key members of management. The tax obligations arose as a result of option exercises pursuant to the terms of the Prior VSOP.
Except for tax obligations, all three members of the management team do not plan to sell additional shares in the foreseeable future.

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CureVac AG

December 14, 2022: Apogenix AG

Apogenix Enrolls First Patients in Pivotal Phase III Trial for the Treatment of Hospitalized COVID-19 Patients with Asunercept

  • The ASUCOV trial assesses efficacy and safety of asunercept on top of standard of care
  • Over 600 patients to be enrolled at 50 trial sites in Europe, India, and South Africa
  • Trial funded by the German Federal Government and dievini Hopp BioTech

Apogenix, a biopharmaceutical company developing next generation immunotherapeutics, announced today that the first patients have been enrolled in a pivotal phase III trial to investigate the efficacy and safety of asunercept on top of standard of care (SoC) for the treatment of hospitalized patients with moderate to severe COVID-19 disease (ASUCOV; NCT05639192). The multicenter, double-blind, placebo-controlled trial aims to enroll more than 600 hospitalized patients requiring oxygen in nine different countries.

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Apogenix AG

December 14, 2022: Cosmo Pharmaceuticals NV

Cosmo announces successful Phase III clinical trial of Lumeblue™ in China

Cosmo Pharmaceuticals N.V. (“Cosmo”) today announced the successful phase III clinical trial of Lumeblue™ in China, sponsored by its partner China Medical System Holdings Limited (CMS) (867.HK).

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Cosmo Pharmaceuticals NV

November 30, 2022: AC Immune SA

AC Immune’s Alzheimer’s Disease Vaccine-candidate ACI-35.030 Selected for Further Development

  • Data presented at CTAD 2022 confirm excellent clinical performance of ACI-35.030 vaccine candidate
  • Based on this new clinical data, ACI-35.030 has been selected for further development representing significant progress for the anti-pTau vaccine candidate
  • AC Immune vaccine portfolio targeting three hallmark proteins of neurodegenerative diseases now progressing through advanced clinical development

AC Immune SA, a clinical-stage biopharmaceutical company pioneering precision medicine for neurodegenerative diseases, today announced that based on the Phase 1b/2a interim data, ACI-35.030, a potential first-in-class anti-phosphorylated-Tau (pTau) vaccine candidate, has been selected for further development. The ACI-35.030 anti-pTau vaccine candidate is being developed in collaboration with Janssen Pharmaceuticals, Inc. (Janssen), part of the Janssen Pharmaceutical Companies of Johnson & Johnson.

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AC Immune SA

November 23, 2022: AC Immune SA

AC Immune to Present Progress of Alzheimer’s Disease Programs targeting Abeta and Tau at the 15th CTAD Conference

  • Next generation SupraAntigen® liposomal vaccine platform augments immunization against pathological targets of Alzheimer’s disease
  • New data on anti-phospho-Tau vaccines confirm safety, tolerability and immunogenicity of ACI-35 and JACI-35, developed in collaboration with Janssen Pharmaceuticals
  • Collaboration partner Genentech/Roche to present pharmacodynamic effects of semorinemab on plasma and CSF Tau biomarkers from “Lauriet” Phase 2 trial in mild-to-moderate Alzheimer’s disease
  • Banner Alzheimer’s Institute to share plasma biomarker data from API-ADAD trial evaluating anti-Abeta antibody crenezumab

AC Immune SA, a clinical-stage biopharmaceutical company pioneering precision medicine for neurodegenerative diseases, today announced the upcoming presentations of its vaccine technology SupraAntigen®, and of its anti-Tau and anti-Abeta investigational candidates, at the 15th Clinical Trials on Alzheimer’s Disease (CTAD) conference in San Francisco, California (United States) and online, on November 29 – December 2, 2022.

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AC Immune SA

November 17, 2022: Immatics Biotechnologies GmbH

Immatics Announces Third Quarter 2022 Financial Results and Business Update

  • Interim clinical update on ACTengine® IMA203 TCR-T monotherapy targeting PRAME demonstrated high confirmed objective response rate (cORR) of 50% (6/12) at or above target dose across Phase 1a and Phase 1b; confirmed responses seen across different solid tumor types: cutaneous melanoma, ovarian cancer, head and neck cancer, uveal melanoma, and synovial sarcoma
  • First patient treated with IMA203CD8, a 2nd generation ACTengine® TCR-T monotherapy product candidate targeting PRAME in Phase 1b expansion cohort C; patient treatment ongoing in all three Phase 1b expansion cohorts
  • Next-generation TCR Bispecific, TCER® IMA402 targeting PRAME showed high anti-tumor activity in vivo, low T cell engager-associated toxicities and favorable pharmacodynamic characteristics in preclinical studies; Phase 1/2 clinical trial on track to start in 2023
  • Joint publication with University of Pennsylvania in Science Translational Medicine on Immatics’ novel proprietary target COL6A3 exon 6
  • $110 million underwritten offering of 10,905,000 ordinary shares successfully completed on Oct 12, 2022
  • Cash and cash equivalents as well as other financial assets of $301.5 million1 (€309.3 million) as of September 30, 2022. Additional cash from the recent public offering in October 2022 funds company operations into 2025

Immatics N.V. (“Immatics”), a clinical-stage biopharmaceutical company active in the discovery and development of T cell-redirecting cancer immunotherapies, today provided a business update and reported financial results for the quarter ended September 30, 2022.

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Immatics Biotechnologies GmbH

November 16, 2022: CureVac AG

CureVac Announces Financial Results for the Third Quarter and First Nine Months of 2022 and Provides Business Update

  • Delivering on broad second-generation vaccine development program with expansion into modified mRNA technology in collaboration with GSK
    • Phase 1 studies in influenza and COVID-19 on track to deliver clinical data in Q1 2023
  • Strengthening oncology position based on preparations for new clinical studies with mRNA-based cancer vaccine candidates and positive Phase 1 data on CV8102
    • Two proof-of-principle studies planned in 2023 to validate and optimize second-generation mRNA backbone in oncology
    • Phase 1 expansion study of non-coding RNA-based candidate CV8102 confirms safety and strong immuno-modulatory characteristics
  • First manufacturing licenses for The RNA Printer® in oncology expected, subject to regulatory approval; applications submitted to regulatory authorities in Q4 2022
  • Driving innovation at the 10th International mRNA Health Conference with data on novel LNP delivery system and therapeutic approaches for diseases with high unmet medical need
  • Cash and cash equivalents position of €540.9 million as of September 30, 2022; driven mainly by proceeds related to transfer of production capacity to GSK

CureVac N.V., a global biopharmaceutical company developing a new class of transformative medicines based on messenger ribonucleic acid (“mRNA”), today announced financial results for the third quarter and first nine months of 2022 and provided a business update.

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CureVac AG
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    • AC Immune SA
    • Apogenix AG
    • Cosmo Pharmaceuticals NV
    • CureVac AG
    • Heidelberg Pharma AG
    • Immatics Biotechnologies GmbH
    • Joimax GmbH
    • Molecular Health GmbH
    • Novaliq GmbH

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